Vestibular Research in Sadeghi Lab

SOROUSH SADEGHI (M.D., Ph.D.), PI
Assistant Professor, Center for Hearing and Balance, Dept. of Otolaryngology - Head and Neck Surgery.
I am interested in understanding the signal transmission properties and compensation/ adaptation observed in the vestibular system. I have studied vestibular system at the systems level in humans (vestibular compensation maneuvers) and non-human primates (in vivo extracellular single unit recording from vestibular afferent fibers and vestibular nuclei neurons) as well as at the cellular level in rats and mice (patch clamp recording from hair cells and afferent terminals). Currently, we use mouse as the mammalian model and use in vitro and in vivo electrophysiology recordings, imaging methods, immunohistochemisty, and pharmacology/ optogenetic stimulation in our research.

Dyllan Zhou, B.A.
VOR, IT and IL injection, in vivo single unit,
VsEP, optogenetic and galvanic stimulation

Daniel Ballinas
VsEP, IT and IL injection

Anant Mashalkar
AI / ML

Yvette Shu
VsEP, IT and IL injection

Jason Cote, Ph.D.
in vitro patch clamp
FORMER MEMBERS
Wesley Schoo, Resident - Otolaryngology
Yaohui Zhu, Ph.D.
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Yugandhar Ramakrishna, Au.D., Ph.D. (In vitro patch clamp recording, VsEP recording, intratympanic (IT) and intralabyrinthine (IL) injections)
Vishal Raghu, Ph.D. (In vivo single unit recording, optical stimulation, VsEP recording, intratympanic (IT) and intralabyrinthine (IL) injections)
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Matthew Johnson, Au.D. (In vitro patch clamp recording)
Eric Tyler, Au.D. (In vivo single unit recording from vestibular nerve afferents)
Julia Murak, Au.D.
Natalie Walsh, Au.D. (In vivo experiments, cfos labeling)​